IL-6 anticorps

N° du produit ABIN289349

L’anticorps Lapin Polyclonal anti-IL-6 a été validé pour WB, ELISA et Inhibition. Il convient pour détecter IL-6 dans des échantillons de Humain.

Aperçu rapide pour IL-6 anticorps (ABIN289349)

Antigène: IL-6 (IL6) (Interleukin 6 (IL6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL-6 est non-conjugé

Application: Western Blotting (WB), ELISA, Blocking Antibody (Inhibition)

Détail du produit anti-IL-6 anticorps

Purification: Purified

Immunogène: IL6 antibody was raised in rabbit using highly pure recombinant hIL-6 as the immunogen.

Information d'application

Indications d'application: ELISA: 0.5-2 µg/mL, Inhibition: 0.2-0.4 µg/mL, WB: 0.1-0.2 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute in sterile water at a concentration of >0.2 mg/mL.

Concentration: Lot specific

Buffer: Lyophilized from PBS, pH 7.2.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

Détails sur IL-6

Antigène: IL-6 (IL6) (Interleukin 6 (IL6))

Autre désignation: IL6

Sujet: IL6 is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, IL6 has diverse biological functions. It stimulates B-cell differentiation and antibody production, synergizes with IL3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. IL6 signals through the IL6 receptor system that consists of two chains, IL6R alpha and gp130. Mouse IL6 is inactive on human cells, while both human and Mouse are equally active on Mouse cells.

Poids moléculaire: 21.7 kDa (predicted detection band MW)

Pathways: Signalisation TLR, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome